"The Freezer/Mill® programmable cryogenic grinder pulverizes through the toughest samples at cryogenic temperatures. Samples are placed in a vial and immersed in a self-contained insulated liquid nitrogen (LN2) tub, reaching cryogenic temperatures in minutes, where they are then pulverized with a magnetically driven impactor. The closed grinding vial impactor prevents sample cross-contamination. The single grinding and cooling chamber allows you to pre-cool and grind two sets of samples simultaneously.
Grind temperature sensitive samples while maintaining constant temperature, as the sample never leaves the enclosed liquid nitrogen bath. Enhanced safety features include a liquid nitrogen sensor and lid interlock. If the lid is opened while in process, grinding will stop. Auto-fill system is available for automated liquid nitrogen filling.
The large, high-resolution touch screen controls all parameters of the run. Store up to 20 user-defined grinding programs for quick and easy recall. The user-friendly interface allows you to view training videos, user manual, and run history, which can be transferred to a computer using a thumb drive.
Purchase liquid nitrogen, extractor, and sample vials separately."
The CG-450 Freezer/Mill is the ultimate solution for grinding tough or temperature-sensitive samples with precision and efficiency. Designed for labs that need high-performance cryogenic processing, this programmable grinder ensures consistent results while protecting sample integrity. The Freezer/Mill accommodates sample sizes ranging from 0.1 to 50 grams.
Typical applications include: DNA/RNA extraction, forensic/drug testing, RoHS/WEEE, consumer product testing, food safety, materials research & medical research.
Typical samples include: animal tissue, plastic and polymers, yeast, pharmaceuticals, food products, electronic components, textiles, hair, teeth, bones, plant tissue such as cannabis, seeds, leaves and roots.
The Cole-Parmer SamplePrep CG-450 Freezer/Mill® is a programmable cryogenic grinder that pulverizes through the toughest samples at cryogenic temperatures. It is ideal for biological, pharmaceutical and food samples, as well as hazardous or critical materials that require safe, efficient processing.
It preserves sample integrity by maintaining constant cryogenic temperatures throughout the grinding process, preventing thermal degradation. Samples are placed in a vial and immersed in a self-contained insulated liquid nitrogen tub, reaching cryogenic temperatures in minutes where they are pulverized with a magnetically driven impactor. Samples remain securely sealed in a closed grinding vial which prevents cross-contamination.
The CG-450 Freezer/Mill provides an effortless and user-friendly design. The high-resolution touchscreen lets you easily set up and store up to 20 grinding programs for easy and quick recall. The user-friendly interface allows you to access integrated training videos, user manual and run history which can be exported to a computer using a USB.
The Freezer/Mill provides powerful and efficient processing. The single grinding and cooling chamber allow pre-cooling and grinding of two sets of samples simultaneously. The CG-450 autofill system automatically transfers liquid nitrogen to the unit during operation, making hand-filling unnecessary. The auto fill mechanism includes a cryogenic valve linked to liquid nitrogen sensors in the tub. When the liquid nitrogen level is low, the valve opens during the precool or cooling stages to let liquid nitrogen into the tub. The auto fill system as supplied also includes a safety valve for the liquid nitrogen transfer hose.
The enhanced safety features of the Cole-Parmer SamplePrep Freezer/Mill include a lid interlock system that stops the grinding process if the lid is opened mid-process. The built-in liquid nitrogen sensor ensures proper cooling, preventing overheating and potential damage. Please note, the mill must be used in an open, well-ventilated area to avoid condensation-related damage. Protective gear including cryogenic gloves and a face shield is recommended when handling liquid nitrogen.
Purchase liquid nitrogen, extractor, and sample vials separately.
Effective September 2023, the Spex SamplePrep 6875A Freeer/Mill® has been rebranded to Cole-Parmer® SamplePrep under model number CG-450 Freezer/Mill®. All the same great features and specification with a new look.
